Fineron 10 | View Uses, Dosage, Interaction, Side-Effects, Price | ePharma
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Fineron 10mg Tablet 10pcs

Generic: Finerenone

Type: Tablet

Pack Size: 10pcs

Finerenone is used to prevent chronic kidney disease.


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Discount Price: ৳ 752
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✅ Description:

Fineron 10mg Tablet contains Finerenone, a non-steroidal mineralocorticoid receptor antagonist. It is prescribed for managing chronic kidney disease (stages 3 and 4) with abnormal levels of albumin (a type of protein) in the urine, associated with type 2 diabetes in adults.

Finerenone blocks the action of certain hormones that can damage the kidneys and heart.

  • Take the tablet as directed by your physician.
  • Swallow with a glass of water; do not crush or chew.
  • Can be taken with or without food.
  • Avoid grapefruit or grapefruit juice while on this medication.
  • Inform your doctor if you have high blood potassium levels.
  • Do not use if allergic to Finerenone or if you have Addison’s disease.
  • Not recommended for pregnant women unless necessary. Use reliable contraception to prevent pregnancy.
  • Avoid use during breastfeeding as it may affect the infant.
  • Avoid combining with certain antibacterial, antifungal, antiviral agents, potassium supplements, antidepressants, and blood pressure medications.

Safety Advices


Alcohol
UNSAFE

No known interactions between Fineron 10 and alcohol. However, moderate consumption is always advised.


Pregnancy
UNSAFE

It is not advisable to use Fineron 10 if you are pregnant unless your doctor determines it is necessary. Inform your doctor if you are pregnant or planning to become pregnant. Women of childbearing potential should use reliable contraception to prevent pregnancy while taking this medicine.


Breastfeeding
UNSAFE

Do not take Kerendia while breastfeeding, as it may pass through breast milk and potentially harm the nursing infant. Consult your doctor before use.


Driving
CAUTION

Kerendia does not affect your ability to drive or operate heavy machinery.


Kidney
CONSULT YOUR DOCTOR

Use with caution in patients with severe kidney impairment or kidney failure. Consult your doctor if you have any concerns.


Liver
CAUTION

Fineron 10 should be used with caution in patients with moderate or severe liver problems. Therefore, consult your doctor before taking it.

Similar Products

✔️ Composition of Fineron 10mg Tablet

Finerenone

✔️ Uses of Fineron 10mg Tablet

Treatment of Chronic kidney disease (CKD)

✔️ Side Effects of Fineron 10mg Tablet

Common Side Effects:

  • High blood potassium, sodium, and uric acid levels.
  • Low blood pressure, which may cause symptoms such as:
    • Nausea
    • Tiredness
    • Weakness
    • Muscle cramps
    • Numbness in hands and feet
    • Dizziness
    • Joint pain
✔️ How does Fineron 10mg Tablet work?

Finerenone in Kerendia tablet blocks aldosterone, a hormone that regulates salt and water balance. This leads to lower blood pressure and relieves strain on the kidneys. It can slow down kidney damage in people with diabetes and chronic kidney disease.

✔️ Quick Suggestions:
  • Fineron 10 is used for managing chronic kidney disease (CKD) in patients with type 2 diabetes.
  • Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, blocks aldosterone effects. Aldosterone can contribute to kidney damage by promoting salt and water retention.
  • Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as there may be interactions with Fineron 10.
  • Not recommended for pregnant or breastfeeding women due to potential risks to the fetus or nursing infant.
  • Take orally with or without food, as directed by your healthcare professional.
  • If a dose is missed, take it as soon as remembered on the same day. Avoid taking double doses.
  • Consider dietary changes and increased physical activity to complement Fineron 10's effects. Discuss these with your healthcare team.
  • If you have any concerns or uncertainties about the medication, consult with your healthcare provider for guidance.
✔️ Indication of Fineron 10mg Tablet
  • Reduces the risk of sustained eGFR decline.
  • Prevents end-stage kidney disease.
  • Reduces cardiovascular death, nonfatal myocardial infarction, and hospitalization for heart failure in adults with chronic kidney disease (CKD) associated with type 2 diabetes (T2D).
✔️ Pharmacology
  • Finerenone is a selective, non-steroidal mineralocorticoid receptor (MR) antagonist.
  • It blocks MR-mediated sodium reabsorption and MR overactivation in tissues such as the kidneys, heart, and blood vessels, which helps mitigate fibrosis and inflammation.
  • Finerenone does not interact with androgen, progesterone, estrogen, or glucocorticoid receptors.
  • It lowers systolic blood pressure by about 3 mmHg and diastolic blood pressure by 1-2 mmHg.
  • Absorption is complete with an absolute bioavailability of 44%. Peak concentration (Cmax) is reached between 0.5 and 1.25 hours post-dose.
  • Steady-state is achieved in 2 days, with steady-state geometric mean Cmax of 160 µg/L and AUCt of 686 µg.h/L at a 20 mg dose.
  • Metabolized primarily by CYP3A4 (90%) and CYP2C8 (10%), with 80% of the dose excreted in urine.
✔️ Dosage & Administration of Fineron 10mg Tablet
  • Starting Dose:
    • eGFR ≥60 mL/min/1.73 m²: 20 mg once daily
    • eGFR ≥25 to <60 mL/min/1.73 m²: 10 mg once daily
    • eGFR <25 mL/min/1.73 m²: Not recommended
  • Dosage Adjustment:
    • Increase to 20 mg after 4 weeks based on eGFR and serum potassium levels.
    • Tablets can be crushed and mixed with water or soft food if needed.
    • Monitor serum potassium 4 weeks after initiation and dose adjustments.
  • Pediatric: Safety and efficacy not established in patients under 18.
  • Geriatric: No dose adjustment is needed for elderly patients.
  • Hepatic Impairment: Avoid in severe hepatic impairment (Child-Pugh C); consider additional monitoring for moderate impairment (Child-Pugh B).
✔️ Interaction
  • Strong CYP3A4 Inhibitors: Avoid use due to increased risk of adverse reactions.
  • Moderate and Weak CYP3A4 Inhibitors: Monitor serum potassium and adjust dosage as needed.
  • Strong and Moderate CYP3A4 Inducers: Avoid use as they reduce Fineron efficacy.
✔️ Contraindications
  • Avoid use with strong CYP3A4 inhibitors.
  • Not suitable for patients with adrenal insufficiency.
✔️ Pregnancy & Lactation
  • Limited data on pregnancy; animal studies show developmental toxicity. Use only if necessary.
  • Avoid breastfeeding due to potential risks to the infant.
✔️ Precautions & Warnings
  • Risk of hyperkalemia, especially with decreased kidney function or high baseline potassium levels.
  • Measure serum potassium and eGFR before and during treatment.
  • Use caution in patients with risk factors for hyperkalemia.
✔️ Storage:

Store below 30°C, away from light and moisture. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Fineron 10 is a medication that is prescribed to reduce the risk of heart attack and heart failure in adult patients who suffer from chronic kidney disease (CKD) associated with type 2 diabetes. The medication works by reducing the retention of salt and water in the body, which helps the heart to work better and, in turn, lowers the risk of heart attacks.

CKD is typically caused by illnesses such as high blood pressure, diabetes, high cholesterol, kidney infections, renal inflammation, recurring kidney stones, an enlarged prostate, and long-term, regular use of certain medications such as lithium and nonsteroidal anti-inflammatory drugs (NSAIDs).

Fineron 10 is typically taken orally with or without food, as directed by a healthcare professional. It's essential to follow the prescribed dosage and instructions carefully.
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Check our pricing section for Fineron 10mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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